Ankyrins. Adaptors between diverse plasma membrane proteins and the cytoplasm.
نویسندگان
چکیده
منابع مشابه
Structural basis of diverse membrane target recognitions by ankyrins
Ankyrin adaptors together with their spectrin partners coordinate diverse ion channels and cell adhesion molecules within plasma membrane domains and thereby promote physiological activities including fast signaling in the heart and nervous system. Ankyrins specifically bind to numerous membrane targets through their 24 ankyrin repeats (ANK repeats), although the mechanism for the facile and in...
متن کاملTargeting and mistargeting of plasma membrane adaptors in vitro
Targeting and recruitment of the plasma membrane (PM) clathrin-coated vesicle adaptor complexes has been studied using an in vitro system based on permeabilized acceptor cells and donor cytosol. Through the use of species- and/or tissue-specific antibodies, only newly recruited exogenous PM adaptors are visualized. Targeting of PM adaptors can be switched from the plasma membrane to a perinucle...
متن کاملEndocytic adaptors--social networking at the plasma membrane.
Receptor-mediated endocytosis is a dynamic process that is crucial for maintaining plasma membrane composition and controlling cell-signaling pathways. A variety of entry routes have evolved to ensure that the vast array of molecules on the cell surface can be differentially internalized by endocytosis. This diversity has extended to include a growing list of endocytic adaptor proteins, which a...
متن کاملThe membrane proteins of the vacuolar system. II. Bidirectional flow between secondary lysosomes and plasma membrane
Lactoperoxidase covalently coupled to latex spheres (LPO-latex) has been used to selectively iodinate the phagolysome (PL) membrane within living macrophages, as discussed in the accompanying article. This procedure labeled approximately 24 polypeptides in the PL membrane; these were similar to those iodinatable on the external surface of the plasma membrane (PM). We now report on the transloca...
متن کاملFunctional Antagonism Between CELF and Mbnl Proteins in the Cytoplasm
Running head: CELF-Mbnl antagonism in cytoplasm and nucleus. CC-BY-NC 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not. Abstract The conserved CUGBP1, Elav-like (CELF) family of RNA binding proteins contribute to heart and skeletal muscle development and are implicated in myotonic dystrophy (DM). To...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1992
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)50333-7